Follow Up

Here's the recent low down.

I was able to get in to do a video conference with my RE earlier than I thought, which was FAB as originally it would have been 8 weeks after the new patient appointment (and the doc requested 3 weeks).  Basically, that CA-125 test wasn't high enough for my RE to have any concerns about it being linked to ovarian cancer but was high enough to show active endometriosis.  That was what I was expecting and it did put my fears to rest.  She DID recommend that I do the endo lap surgery now (yep, EXACTLY what I said I needed) and to do IVF the next cycle after.  She went ahead and ordered a ton more blood work for a recurrent miscarriage panel (hello another 13 vials of blood).  I got the results as we were out of town in Houston. 

Everything was in normal range except two.  I was not surprised in the least to know that I have the MTHFR gene mutation (c677T single mutation, heterozygous) but I was shocked to learn that I also have PAI-1 4G/5G deletion/insertion allele promoter polymorphism (also heterozygous, one copy of each).  The two of those mutation together is more cause for concern vs. just having one.  Guess what?  It causes recurrent miscarriages and implantation failure due to clotting factors. I was told that if I was to get preg naturally (uh huh it's been 4 years my friends) that I'd need to call them the minute I find out so I can be put on Lovenox/Heparin and low dose aspirin to thin my blood.  If I do IVF, I'll be put on those for my entire cycle.  I'm surprised I wasn't tested for these things sooner...but I guess it's good I'm finally getting some answers. So, not only do I have a really hard time getting preg, I have an even harder time staying preg.

My AMH (Anti-Mullerian hormone) level is decent for my age.  Anything over 1.06 is correlated with a better response to ovarian stimulation, so that's good for my chances with IVF. 

Next week is my consult with Dr. B.  I'll keep you posted....